2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13836
    ELQ-300
    		Inhibitor ≥98.0%
    ELQ-300 is a potent and orally bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1). ELQ-300 inhibits growth of P. falciparum Dd2, Tm90-C2B, and D1 with IC50 values of 6.6, 4.6 and 160 nM, respectively. ELQ-300 can be used for the research of antimalarial.
    ELQ-300
  • HY-111746
    CWHM-1008
    		Inhibitor 99.06%
    CWHM-1008 is a potent and orally active antimalarial agent, with EC50 values of 46 and 21 nM against agent-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively.
    CWHM-1008
  • HY-111759
    Jaspamycin
    		Inhibitor 98.60%
    Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity.
    Jaspamycin
  • HY-B1244
    Dimetridazole
    		Inhibitor 99.80%
    Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections.
    Dimetridazole
  • HY-116448
    Metaflumizone
    		Inhibitor
    Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
    Metaflumizone
  • HY-111817
    ACT-451840
    		Inhibitor
    ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial.
    ACT-451840
  • HY-B1636
    Dithiazanine iodide
    		Inhibitor 99.91%
    Dithiazanine iodide is an effective broad-spectrum anthelmintic. Dithiazanine iodide can be used for the research of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. Dithiazanine iodide is also a cyanine dye.
    Dithiazanine iodide
  • HY-B0846
    Dimethomorph
    		99.13%
    Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM.
    Dimethomorph
  • HY-151561
    WM382
    		Inhibitor 99.35%
    WM382 is an orally active and potent dual plasmepsin IX/X (PMIX/X) inhibitor with IC50 values of 1.4 nM and 0.03 nM, respectively. WM382 has robust in vivo efficacy at multiple stages of the malaria parasite life cycle and an excellent resistance profile.
    WM382
  • HY-117015
    Purfalcamine
    		Inhibitor 99.44%
    Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage.
    Purfalcamine
  • HY-N9343
    Kulactone
    		Inhibitor 98.25%
    Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB).
    Kulactone
  • HY-N6009
    8-Deoxygartanin
    		Inhibitor 99.24%
    8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE). 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM.
    8-Deoxygartanin
  • HY-15648C
    GSK-J5
    		Inhibitor 99.96%
    GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner.
    GSK-J5
  • HY-N1581
    Quassin
    		Inhibitor ≥98.0%
    Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
    Quassin
  • HY-W103183
    Ferron
    		99.43%
    Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) has antiseptic and antifungal activity. Ferron can prevent skin and mucosa bacterial irritations and inflammations.
    Ferron
  • HY-16762
    Artefenomel
    		Inhibitor 99.14%
    Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2.
    Artefenomel
  • HY-N4106
    Dihydroartemisinic acid
    		Inhibitor 99.58%
    Dihydroartemisinic acid (Dihydroqinghao acid) is a biosynthetic precursor to the antimalarial agent Artemisinin.
    Dihydroartemisinic acid
  • HY-112542
    Nemadectin
    		Inhibitor 99.79%
    Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
    Nemadectin
  • HY-114489A
    Haemanthamine
    		Inhibitor
    Haemanthamine is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities.
    Haemanthamine
  • HY-B1896A
    Piperaquine phosphate
    		Inhibitor 98.33%
    Piperaquine phosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin.
    Piperaquine phosphate
Parasite Isoform Comparison

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